Ipo7 | importin 7

GeneMGI:2152414Synonyms: A330055O14Rik, Imp7, +1 more

Physiological systems

23 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Respiratory system Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system

13 No significant impact

1 Not tested

Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetIpo7em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsIpo7em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal lymph node morphology2 supporting datasetsIpo7em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal spleen morphology1 supporting datasetIpo7em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged spleen1 supporting datasetIpo7em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged lymph nodes1 supporting datasetIpo7em1(IMPC)MbpheterozygoteLate adultN/A * 
increased exploration in new environment1 supporting datasetIpo7em1(IMPC)MbpheterozygoteLate adult8.65x10-5 
abnormal skin morphology1 supporting datasetIpo7em1(IMPC)MbpheterozygoteLate adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsIpo7em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating phosphate level1 supporting datasetIpo7em1(IMPC)MbpheterozygoteEarly adult2.74x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ipo7em1(IMPC)MbpExon Deletionmouse

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