Lrp1b | low density lipoprotein-related protein 1B

GeneMGI:2151136Synonyms: 9630004P12Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating iron level	1 supporting dataset	Lrp1b^{em1(IMPC)Hmgu}	heterozygote	Early adult	6.76x10^-8
decreased circulating unsaturated transferrin level	1 supporting dataset	Lrp1b^{em1(IMPC)Hmgu}	heterozygote	Early adult	8.94x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Lrp1b^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
increased food intake	1 supporting dataset	Lrp1b^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.31x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrp1b.

Associated images

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Histopathology

There is no histopathology data found for Lrp1b.

IMPC related publications

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External links

No external links available for Lrp1b.

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*Lrp1b^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Lrp1b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lrp1b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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