Adarb2 | adenosine deaminase, RNA-specific, B2

GeneMGI:2151118Synonyms: RED2, Adar3

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal coat/ hair morphology	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	1.28x10^-7
small kidney	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
limb grasping	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	2.42x10^-6
decreased bone mineral density	1 supporting dataset	Adarb2^em1(IMPC)Tcp	homozygote	Early adult	6.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adarb2.

Associated images

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Histopathology

There is no histopathology data found for Adarb2.

IMPC related publications

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External links

No external links available for Adarb2.

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*Adarb2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Adarb2^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Adarb2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adarb2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Adarb2^{tm2(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Adarb2^{tm42060(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Adarb2^{tm42060(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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