Rnf123 | ring finger protein 123

GeneMGI:2148796Synonyms: KPC1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular hemoglobin	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	6.63x10^-10
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	1.5x10^-24
increased fasting circulating glucose level	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	4.52x10^-6
hyperactivity	4 supporting datasets	Rnf123^em1(IMPC)J	homozygote	Early adult	3.47x10^-5
decreased mean corpuscular volume	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	2.27x10^-11
abnormal auditory brainstem response	2 supporting datasets	Rnf123^em1(IMPC)J	homozygote	Early adult	4.23x10^-5
increased hemoglobin content	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	1.74x10^-5
improved glucose tolerance	1 supporting dataset	Rnf123^em1(IMPC)J	homozygote	Early adult	1.72x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf123.

Associated images

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Histopathology

There is no histopathology data found for Rnf123.

IMPC related publications

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External links

No external links available for Rnf123.

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*Rnf123^em1(IMPC)J*	Exon Deletion	‌	mouse
*Rnf123^{tm376734(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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