Drgx | dorsal root ganglia homeobox

GeneMGI:2148204Synonyms: Prrxl1, Drg11

Physiological systems

22 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Embryo Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

10 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
small kidney	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	3.66x10^-6
abnormal testis morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged testis	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal uterus morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal placenta morphology	1 supporting dataset	Drgx^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Drgx.

Associated images

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Histopathology

There is no histopathology data found for Drgx.

IMPC related publications

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External links

No external links available for Drgx.

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*Drgx^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Drgx^{tm91588(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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