Nexmif | neurite extension and migration factor

GeneMGI:2148050Synonyms: Xpn, C77370

Physiological systems

17 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

7 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:21Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



male infertility	1 supporting dataset	Nexmif^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	4.18x10^-5
increased mean corpuscular volume	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	0
abnormal sternum morphology	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	4.44x10^-16
hyperactivity	8 supporting datasets	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	0
decreased bone mineral content	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	2.17x10^-5
increased circulating triglyceride level	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	3.61x10^-5
enlarged urinary bladder	1 supporting dataset	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	N/A ^*
increased eosinophil cell number	2 supporting datasets	Nexmif^em1(IMPC)Tcp	hemizygote	Early adult	8.47x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nexmif.

Associated images

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Histopathology

There is no histopathology data found for Nexmif.

IMPC related publications

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External links

No external links available for Nexmif.

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*Nexmif^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Nexmif^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

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