Lrch2 | leucine-rich repeats and calponin homology (CH) domain containing 2

GeneMGI:2147870

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eye morphology	1 supporting dataset	Lrch2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	Lrch2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Lrch2^em1(IMPC)Mbp	homozygote	Early adult	6.92x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrch2.

Associated images

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Histopathology

There is no histopathology data found for Lrch2.

IMPC related publications

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External links

No external links available for Lrch2.

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*Lrch2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Lrch2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lrch2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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