Tmem132a | transmembrane protein 132A

GeneMGI:2147810Synonyms: Hspa5bp1, 6720481D13Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Adipose tissue Embryo Growth/size/body region Limbs/digits/tail Nervous system Behavior/neurological Skeleton Craniofacial Mortality/aging

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal limb morphology	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
increased total body fat amount	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.7x10^-5
abnormal limb morphology	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
syndactyly	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
abnormal head shape	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
abnormal tail morphology	2 supporting datasets	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	heterozygote	E18.5	N/A ^*
abnormal facial morphology	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
abnormal cranium morphology	1 supporting dataset	Tmem132a^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem132a.

Associated images

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Histopathology

There is no histopathology data found for Tmem132a.

IMPC related publications

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External links

No external links available for Tmem132a.

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*Tmem132a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tmem132a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem132a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Tmem132a^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tmem132a^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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