Kank1 | KN motif and ankyrin repeat domains 1

GeneMGI:2147707Synonyms: Ankrd15, D330024H06Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Nervous system Vision/eye

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition1 supporting datasetKank1em1(IMPC)BayhomozygoteEarly adult6.82x10-6 
abnormal eye anterior chamber depth1 supporting datasetKank1em1(IMPC)BayhomozygoteEarly adult1.52x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Kank1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Kank1em1(IMPC)BayExon Deletionmouse
Kank1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kank1tm371778(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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