Patl1 | protein associated with topoisomerase II homolog 1 (yeast)
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Behavior/neurological Mortality/aging
17 No significant impact
3 Not tested
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| decreased grip strength | 4 supporting datasets | Patl1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.03x10-15 | ||
| decreased prepulse inhibition | 3 supporting datasets | Patl1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.54x10-6 | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Patl1tm1b(EUCOMM)Wtsi | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Patl1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| tremors | 1 supporting dataset | Patl1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.18x10-5 | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Patl1tm1b(EUCOMM)Wtsi | heterozygote | E18.5 | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Patl1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.92x10-5 | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Patl1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Patl1.
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| Patl1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Patl1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Patl1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |