Uqcc3 | ubiquinol-cytochrome c reductase complex assembly factor 3

GeneMGI:2147553Synonyms: Cbp4, AI462493

Physiological systems

14 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hearing/vestibular/ear Cardiovascular system Mortality/aging Craniofacial

5 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal otic vesicle morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal hindbrain development	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Uqcc3^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal visceral yolk sac morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal tail bud morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal pharyngeal arch morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal heart looping	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Uqcc3^em1(IMPC)Bay	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Uqcc3.

Associated images

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Histopathology

There is no histopathology data found for Uqcc3.

IMPC related publications

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External links

No external links available for Uqcc3.

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*Uqcc3^em1(IMPC)Bay*	Whole-gene deletion	‌	mouse
*Uqcc3^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Uqcc3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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