Fhip2a | FHF complex subunit HOOK interacting protein 2A
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal locomotor behavior | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 1.92x10-9 | ||
| abnormal bone structure | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 8.67x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 2.44x10-14 | ||
| impaired glucose tolerance | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 6.9x10-6 | ||
| abnormal optic disk morphology | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 1.49x10-7 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Fhip2aem1(IMPC)J | homozygote | Early adult | 2.83x10-12 |
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Human diseases caused by Fhip2a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fhip2a.
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| Fhip2aem1(IMPC)J | Exon Deletion | | mouse |