Abhd3 | abhydrolase domain containing 3

GeneMGI:2147183Synonyms: LABH3

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Muscle Behavior/neurological Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

dilated heart left ventricle1 supporting datasetAbhd3em1(IMPC)MarchomozygoteEarly adult6.18x10-5 
thin ventricular wall1 supporting datasetAbhd3em1(IMPC)MarchomozygoteEarly adult6.4x10-5 
decreased exploration in new environment1 supporting datasetAbhd3em1(IMPC)MarchomozygoteEarly adult2.02x10-5 
decreased locomotor activity1 supporting datasetAbhd3em1(IMPC)MarchomozygoteEarly adult9.6x10-5 
decreased heart left ventricle size1 supporting datasetAbhd3em1(IMPC)MarchomozygoteEarly adult4.9x10-6 
decreased cardiac muscle contractility2 supporting datasetsAbhd3em1(IMPC)MarchomozygoteEarly adult2.4x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Abhd3em1(IMPC)MarcIndelmouse
Abhd3tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Abhd3tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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