Brpf3 | bromodomain and PHD finger containing, 3

GeneMGI:2146836

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Brpf3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	Brpf3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.4x10^-5
decreased circulating potassium level	1 supporting dataset	Brpf3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.32x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brpf3.

Associated images

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Histopathology

There is no histopathology data found for Brpf3.

IMPC related publications

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External links

No external links available for Brpf3.

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*Brpf3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Brpf3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Brpf3^{tm39782(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes