P3h2 | prolyl 3-hydroxylase 2

GeneMGI:2146663Synonyms: Leprel1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Behavior/neurological Craniofacial

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal snout morphology1 supporting datasetP3h2em1(IMPC)HheterozygoteEarly adult1.32x10-9 
increased circulating potassium level1 supporting datasetP3h2em1(IMPC)HhomozygoteEarly adult9.24x10-6 
decreased circulating fructosamine level1 supporting datasetP3h2em1(IMPC)HhomozygoteEarly adult2x10-5 
decreased locomotor activity1 supporting datasetP3h2em1(IMPC)HhomozygoteEarly adult8.35x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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P3h2em1(IMPC)HExon Deletionmouse
P3h2em2(IMPC)HExon Deletionmouse
P3h2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
P3h2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
P3h2tm92882(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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