Dock10 | dedicator of cytokinesis 10

GeneMGI:2146320Synonyms: Jr4, 9330153B10Rik, +4 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased T cell number	1 supporting dataset	Dock10^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.93x10^-5
abnormal behavior	3 supporting datasets	Dock10^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.17x10^-6
increased circulating cholesterol level	1 supporting dataset	Dock10^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.47x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dock10.

Associated images

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Histopathology

There is no histopathology data found for Dock10.

IMPC related publications

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External links

No external links available for Dock10.

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*Dock10^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dock10^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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