Alg10b | ALG10 alpha-1,2-glucosyltransferase

GeneMGI:2146159Synonyms: nse5, LOC380959, +1 more

Physiological systems

18 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hearing/vestibular/ear Cardiovascular system Mortality/aging Craniofacial

7 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



bleb	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal optic vesicle formation	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal somite shape	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
increased body temperature	1 supporting dataset	Alg10b^{tm1(KOMP)Vlcg}	heterozygote	Early adult	9.39x10^-7
abnormal pericardium morphology	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal allantois morphology	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal vitelline vasculature morphology	1 supporting dataset	Alg10b^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Alg10b.

Associated images

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Histopathology

There is no histopathology data found for Alg10b.

IMPC related publications

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External links

No external links available for Alg10b.

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*Alg10b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Alg10b^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Alg10b^{tm2(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Alg10b^{tm298616(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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