Agxt2 | alanine-glyoxylate aminotransferase 2

GeneMGI:2146052

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hearing/vestibular/ear Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Agxt2^{em1(IMPC)Hmgu}	heterozygote	Early adult	9.85x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Agxt2^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Agxt2.

Associated images

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Histopathology

There is no histopathology data found for Agxt2.

IMPC related publications

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External links

No external links available for Agxt2.

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*Agxt2^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Agxt2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Agxt2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Agxt2^{tm42687(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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