Ano6 | anoctamin 6

GeneMGI:2145890Synonyms: Tmem16f, 2900059G15Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Cardiovascular system Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal cholesterol homeostasis1 supporting datasetAno6em3(IMPC)TcpheterozygoteEarly adult6.19x10-11 
enlarged lymph nodes1 supporting datasetAno6em3(IMPC)TcpheterozygoteEarly adultN/A * 
shortened PQ interval1 supporting datasetAno6em3(IMPC)TcpheterozygoteEarly adult6.17x10-5 
preweaning lethality, incomplete penetrance3 supporting datasetsAno6em3(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ano6em3(IMPC)TcpIndelmouse
Ano6tm442763(L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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