Ccno | cyclin O

GeneMGI:2145534Synonyms: Ung2, Ccnu

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Renal/urinary system

19 No significant impact

4 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology2 supporting datasetsCcnoem1(IMPC)MbpheterozygoteEarly adultN/A * 
small kidney2 supporting datasetsCcnoem1(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Ccno mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Ccnoem1(IMPC)MbpWhole-gene deletionmouse
Ccnotm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ccnotm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ccnotm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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