Lrfn5 | leucine rich repeat and fibronectin type III domain containing 5

GeneMGI:2144814

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased neutrophil cell number	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	8.13x10^-5
abnormal eye morphology	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal retina vasculature morphology	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	1.89x10^-6
increased erythrocyte cell number	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	9.77x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	2.05x10^-6
decreased thigmotaxis	2 supporting datasets	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	1.36x10^-8
decreased mean corpuscular hemoglobin	1 supporting dataset	Lrfn5^em1(IMPC)Tcp	homozygote	Early adult	1.11x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrfn5.

Associated images

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Histopathology

There is no histopathology data found for Lrfn5.

IMPC related publications

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External links

No external links available for Lrfn5.

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*Lrfn5^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Lrfn5^{tm45769(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Lrfn5^{tm45769(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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