Tedc1 | tubulin epsilon and delta complex 1

GeneMGI:2144738Synonyms: 4930427A07Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Embryo Growth/size/body region Mortality/aging Cardiovascular system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal heart morphology	1 supporting dataset	Tedc1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
enlarged lymph nodes	2 supporting datasets	Tedc1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Tedc1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Tedc1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Tedc1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Tedc1^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Tedc1^em1(IMPC)Tcp	heterozygote	Early adult	5.61x10^-5
embryonic growth retardation	1 supporting dataset	Tedc1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
abnormal skin morphology	2 supporting datasets	Tedc1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Tedc1^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tedc1.

Associated images

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Histopathology

There is no histopathology data found for Tedc1.

IMPC related publications

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External links

No external links available for Tedc1.

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*Tedc1^em1(IMPC)Tcp*	Deletion	‌	mouse
*Tedc1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Tedc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tedc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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