Ttc7b | tetratricopeptide repeat domain 7B

GeneMGI:2144724Synonyms: Ttc7l1

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Pigmentation Integument Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prenatal lethality1 supporting datasetTtc7bem1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetTtc7bem1(IMPC)JhomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetTtc7bem1(IMPC)JhomozygoteE15.5N/A * 
abnormal coat/hair pigmentation1 supporting datasetTtc7bem1(IMPC)JheterozygoteEarly adult4.9x10-5 
abnormal vocalization1 supporting datasetTtc7bem1(IMPC)JheterozygoteEarly adult1.48x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ttc7bem1(IMPC)JExon Deletionmouse
Ttc7btm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ttc7btm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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