Usp32 | ubiquitin specific peptidase 32

GeneMGI:2144475Synonyms: 2900074J03Rik, 6430526O11Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased red blood cell distribution width	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	7.28x10^-5
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	1.62x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	homozygote	Early adult	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	8.33x10^-5
increased leukocyte cell number	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	9.3x10^-5
decreased circulating glucose level	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	5.47x10^-8
increased mean corpuscular volume	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	4.71x10^-22
decreased neutrophil cell number	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	4.81x10^-5
thrombocytosis	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	4.61x10^-9
increased lymphocyte cell number	1 supporting dataset	Usp32^{em1(IMPC)Mhzh}	heterozygote	Early adult	5.04x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp32.

Associated images

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Histopathology

There is no histopathology data found for Usp32.

IMPC related publications

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External links

No external links available for Usp32.

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*Usp32^{em1(IMPC)Mhzh}*	Deletion	‌	mouse
*Usp32^{tm119273(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Usp32^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Usp32^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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