Jmjd4 | jumonji domain containing 4

Physiological systems

16 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton Craniofacial

9 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating fructosamine level1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult1.2x10-6 
increased leukocyte cell number1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult8.37x10-5 
decreased fasting circulating glucose level1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult3.25x10-8 
increased mean corpuscular hemoglobin1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult4.04x10-5 
abnormal incisor morphology1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult8.02x10-6 
increased circulating alkaline phosphatase level1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult1.47x10-5 
decreased total body fat amount1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult1.08x10-5 
increased lean body mass1 supporting datasetJmjd4em1(IMPC)WtsihomozygoteEarly adult5.94x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Jmjd4em1(IMPC)WtsiDeletionmouse
Jmjd4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Jmjd4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Jmjd4tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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