Ccdc117 | coiled-coil domain containing 117

GeneMGI:2144383Synonyms: 1700026O03Rik, 1110004K02Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response1 supporting datasetCcdc117em1(IMPC)JhomozygoteEarly adult9.23x10-7 
increased grip strength2 supporting datasetsCcdc117em1(IMPC)JhomozygoteEarly adult9.79x10-8 
increased startle reflex1 supporting datasetCcdc117em1(IMPC)JhomozygoteEarly adult8.11x10-6 
increased circulating alkaline phosphatase level1 supporting datasetCcdc117em1(IMPC)JhomozygoteEarly adult4.05x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccdc117em1(IMPC)JExon Deletionmouse
Ccdc117tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ccdc117tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ccdc117tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ccdc117tm214189(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector
Ccdc117tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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