Nsrp1 | nuclear speckle regulatory protein 1

GeneMGI:2144305Synonyms: NSpr70, Ccdc55

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Vision/eye Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal retina morphology	1 supporting dataset	Nsrp1^em1(IMPC)Mbp	heterozygote	Early adult	8.04x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Nsrp1^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
decreased circulating phosphate level	1 supporting dataset	Nsrp1^em1(IMPC)Mbp	heterozygote	Early adult	8.56x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Nsrp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Nsrp1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nsrp1.

Associated images

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Histopathology

There is no histopathology data found for Nsrp1.

IMPC related publications

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External links

No external links available for Nsrp1.

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*Nsrp1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Nsrp1^{tm239028(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Nsrp1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nsrp1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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