L3mbtl3 | L3MBTL3 histone methyl-lysine binding protein
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Craniofacial Mortality/aging
12 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal embryo size | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| polydactyly | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | heterozygote | E15.5 | N/A * | ||
| abnormal craniofacial morphology | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | L3mbtl3em2(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | L3mbtl3em2(IMPC)Tcp | heterozygote | Early adult | N/A * |
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External links
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| L3mbtl3em2(IMPC)Tcp | Exon Deletion | | mouse |
| L3mbtl3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| L3mbtl3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |