Dis3l | DIS3 like exosome 3'-5' exoribonuclease

GeneMGI:2143272

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	1 supporting dataset	Dis3l^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
thick ventricular wall	1 supporting dataset	Dis3l^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.19x10^-5
enlarged kidney	1 supporting dataset	Dis3l^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Dis3l^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Dis3l^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dis3l.

Associated images

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Histopathology

There is no histopathology data found for Dis3l.

IMPC related publications

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External links

No external links available for Dis3l.

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*Dis3l^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse

My Genes