Xylb | xylulokinase homolog (H. influenzae)

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	2 supporting datasets	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.04x10^-12
abnormal startle reflex	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.7x10^-7
abnormal response to tactile stimuli	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.52x10^-8
increased total body fat amount	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.97x10^-11
decreased prepulse inhibition	3 supporting datasets	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.76x10^-5
tremors	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	9.11x10^-6
decreased lactate dehydrogenase level	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.88x10^-5
increased bone mineral content	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.3x10^-10
decreased circulating alkaline phosphatase level	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.03x10^-10
abnormal bone mineralization	1 supporting dataset	Xylb^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.16x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Xylb.

Associated images

Loading...

Histopathology

There is no histopathology data found for Xylb.

IMPC related publications

Loading...

External links

No external links available for Xylb.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Xylb^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Xylb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Xylb^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes