Edc3 | enhancer of mRNA decapping 3

GeneMGI:2142951Synonyms: Yjdc, Lsm16

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Hematopoietic system Renal/urinary system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal skin morphology	2 supporting datasets	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
single kidney	1 supporting dataset	Edc3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	1.2x10^-5
abnormal testis morphology	1 supporting dataset	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
increased mean platelet volume	1 supporting dataset	Edc3^em1(IMPC)Tcp	homozygote	Early adult	8.32x10^-6
decreased prepulse inhibition	1 supporting dataset	Edc3^em1(IMPC)Tcp	homozygote	Early adult	3.93x10^-5
enlarged lymph nodes	2 supporting datasets	Edc3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Edc3.

Associated images

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Histopathology

There is no histopathology data found for Edc3.

IMPC related publications

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External links

No external links available for Edc3.

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*Edc3^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Edc3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Edc3^{tm78954(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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