Cog4 | component of oligomeric golgi complex 4

GeneMGI:2142808Synonyms: D8Ertd515e

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Behavior/neurological Skeleton Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Cog4^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Cog4^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
decreased bone mineral density	1 supporting dataset	Cog4^em1(IMPC)Bay	heterozygote	Early adult	3.1x10^-5
increased bone mineral content	2 supporting datasets	Cog4^em1(IMPC)Bay	heterozygote	Early adult	5.31x10^-7
hyperactivity	1 supporting dataset	Cog4^em1(IMPC)Bay	heterozygote	Late adult	3.17x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cog4.

Associated images

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Histopathology

There is no histopathology data found for Cog4.

IMPC related publications

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External links

No external links available for Cog4.

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*Cog4^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Cog4^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cog4^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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