Ces1f | carboxylesterase 1F

GeneMGI:2142687Synonyms: TGH-2, CesML1

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Hearing/vestibular/ear Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetCes1ftm1b(KOMP)WtsihomozygoteEarly adult1.84x10-8 
abnormal auditory brainstem response1 supporting datasetCes1ftm1b(KOMP)WtsihomozygoteEarly adult1.37x10-5 
abnormal skin coloration1 supporting datasetCes1ftm1b(KOMP)WtsihomozygoteEarly adult3.38x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ces1ftm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ces1ftm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ces1ftm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Ces1ftm42900(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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