Alg11 | ALG11 alpha-1,2-mannosyltransferase

GeneMGI:2142632

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased grip strength	2 supporting datasets	Alg11^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.7x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Alg11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Alg11^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.49x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Alg11^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Alg11.

Associated images

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Histopathology

There is no histopathology data found for Alg11.

IMPC related publications

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External links

No external links available for Alg11.

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*Alg11^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Alg11^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Alg11^{tm112029(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Alg11^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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