Alkbh6 | alkB homolog 6

GeneMGI:2142037Synonyms: Abh6

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eye morphology	1 supporting dataset	Alkbh6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating creatinine level	1 supporting dataset	Alkbh6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.14x10^-6
increased circulating alanine transaminase level	1 supporting dataset	Alkbh6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.03x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Alkbh6.

Associated images

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Histopathology

There is no histopathology data found for Alkbh6.

IMPC related publications

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External links

No external links available for Alkbh6.

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*Alkbh6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Alkbh6^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Alkbh6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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