Prkd2 | protein kinase D2

GeneMGI:2141917Synonyms: PKD2

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	5 supporting datasets	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.18x10^-11
increased circulating alanine transaminase level	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.56x10^-5
abnormal brain morphology	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.52x10^-6
decreased food intake	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	2.59x10^-5
decreased respiratory quotient	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	2.71x10^-5
decreased startle reflex	1 supporting dataset	Prkd2^{em1(IMPC)Hmgu}	homozygote	Early adult	2.22x10^-18

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prkd2.

Associated images

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Histopathology

There is no histopathology data found for Prkd2.

IMPC related publications

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External links

No external links available for Prkd2.

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*Prkd2^{em1(IMPC)Hmgu}*	Intra-exon deletion	‌	mouse
*Prkd2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes