Ric8a | RIC8 guanine nucleotide exchange factor A
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Adipose tissue Vision/eye Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| persistence of hyaloid vascular system | 1 supporting dataset | Ric8atm1b(KOMP)Wtsi | heterozygote | Early adult | 2.81x10-5 | ||
| impaired pupillary reflex | 1 supporting dataset | Ric8atm1b(KOMP)Wtsi | heterozygote | Early adult | 6.03x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ric8atm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Ric8atm1b(KOMP)Wtsi | heterozygote | Early adult | 1.13x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ric8atm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Ric8a.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ric8atm119201(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Ric8atm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ric8atm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ric8atm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |