Ap2s1 | adaptor-related protein complex 2, sigma 1 subunit
GeneMGI:2141861
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Growth/size/body region Digestive/alimentary Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased body length | 1 supporting dataset | Ap2s1em1(IMPC)Tcp | heterozygote | Early adult | 3.15x10-15 | ||
| abnormal cecum morphology | 1 supporting dataset | Ap2s1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| enlarged cecum | 1 supporting dataset | Ap2s1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ap2s1em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ap2s1em1(IMPC)Tcp | homozygote | E12.5 | N/A * |
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External links
No external links available for Ap2s1.
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| Ap2s1em1(IMPC)Tcp | Intra-exon deletion | | mouse |
| Ap2s1tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Ap2s1tm454684(L1L2_GT0_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |