Glmn | glomulin, FKBP associated protein
Physiological systems
17 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Integument Embryo Growth/size/body region Limbs/digits/tail Nervous system Mortality/aging Cardiovascular system Craniofacial
9 No significant impact
7 Not tested
Data collections
Gene metrics:23Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal visceral yolk sac morphology | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal vitelline vasculature morphology | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Glmnem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal tail bud morphology | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal pharyngeal arch morphology | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal hindbrain development | 1 supporting dataset | Glmnem1(IMPC)Bay | homozygote | E9.5 | N/A * |
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Human diseases caused by Glmn mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Glmn.
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| Glmnem1(IMPC)Bay | Exon Deletion | | mouse |
| Glmntm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Glmntm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Glmntm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |