AU040320 | expressed sequence AU040320
GeneMGI:2140475
Physiological systems
17 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Pigmentation Integument Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton
9 No significant impact
7 Not tested
Data collections
Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased bone mineral density | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Early adult | 2.37x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Late adult | 8.64x10-12 | ||
| hyperactivity | 6 supporting datasets | AU040320em1(IMPC)J | homozygote | Late adult | 2.26x10-9 | ||
| hyperactivity | 5 supporting datasets | AU040320em1(IMPC)J | homozygote | Early adult | 6.27x10-7 | ||
| decreased grip strength | 2 supporting datasets | AU040320em1(IMPC)J | homozygote | Late adult | 1.13x10-9 | ||
| limb grasping | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Late adult | 3.28x10-7 | ||
| decreased bone mineral content | 2 supporting datasets | AU040320em1(IMPC)J | homozygote | Early adult | 4.5x10-6 | ||
| increased exploration in new environment | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Late adult | 2.28x10-9 | ||
| absent vibrissae | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Late adult | 1.74x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | AU040320em1(IMPC)J | homozygote | Early adult | 4.19x10-7 |
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Human diseases caused by AU040320 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for AU040320.
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| AU040320em1(IMPC)J | Exon Deletion | | mouse |
| AU040320tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| AU040320tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| AU040320tm497(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| AU040320tm497(L1L2_st1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |