Eps8l3 | EPS8-like 3
GeneMGI:2139743
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Skeleton Craniofacial
15 No significant impact
7 Not tested
Data collections
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal cranium morphology | 1 supporting dataset | Eps8l3tm1b(KOMP)Mbp | homozygote | Early adult | 4.29x10-5 | ||
| abnormal maxilla morphology | 1 supporting dataset | Eps8l3tm1b(KOMP)Mbp | homozygote | Early adult | 1.08x10-5 |
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Human diseases caused by Eps8l3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Eps8l3.
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| Eps8l3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Eps8l3tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Eps8l3tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Eps8l3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |