Fastkd5 | FAST kinase domains 5

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetFastkd5tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal sleep behavior1 supporting datasetFastkd5em1(IMPC)JhomozygoteEarly adult2.41x10-6 
embryonic lethality prior to organogenesis1 supporting datasetFastkd5tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
shortened QRS complex duration1 supporting datasetFastkd5em1(IMPC)JhomozygoteEarly adult1.38x10-5 
impaired righting response1 supporting datasetFastkd5em1(IMPC)JhomozygoteEarly adult4.66x10-5 
decreased circulating glucose level1 supporting datasetFastkd5em1(IMPC)JhomozygoteEarly adult7.14x10-5 
preweaning lethality, complete penetrance1 supporting datasetFastkd5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fastkd5em1(IMPC)JIndelmouse
Fastkd5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fastkd5tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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