Snph | syntaphilin
GeneMGI:2139270
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Growth/size/body region Nervous system Behavior/neurological Skeleton
17 No significant impact
3 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased bone mineral content | 1 supporting dataset | Snphtm1.1(KOMP)Vlcg | homozygote | Early adult | 5.25x10-5 | ||
| hyperactivity | 1 supporting dataset | Snphtm1.1(KOMP)Vlcg | homozygote | Early adult | 5.15x10-5 | ||
| decreased body length | 1 supporting dataset | Snphtm1.1(KOMP)Vlcg | homozygote | Early adult | 5.27x10-6 | ||
| decreased brain weight | 1 supporting dataset | Snphtm1.1(KOMP)Vlcg | homozygote | Early adult | 8.98x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
Human diseases caused by Snph mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Snph.
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