Chst10 | carbohydrate sulfotransferase 10
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Adipose tissue Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological
14 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased thigmotaxis | 2 supporting datasets | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 5.41x10-6 | ||
| increased spleen weight | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 8.37x10-5 | ||
| decreased locomotor activity | 2 supporting datasets | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 5.66x10-5 | ||
| decreased total retina thickness | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 3.31x10-9 | ||
| decreased total body fat amount | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 7.8x10-5 | ||
| abnormal behavior | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 5.41x10-6 | ||
| increased red blood cell distribution width | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 9.23x10-7 | ||
| decreased anxiety-related response | 1 supporting dataset | Chst10em1(IMPC)Hmgu | homozygote | Early adult | 1.4x10-5 |
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Human diseases caused by Chst10 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Chst10.
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| Chst10em1(IMPC)Hmgu | Exon Deletion | | mouse |
| Chst10tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |