Zfp451 | zinc finger protein 451

GeneMGI:2137896Synonyms: Kiaa0576-hp, 4933435G09Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Endocrine/exocrine gland Integument Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal pancreas morphology	1 supporting dataset	Zfp451^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Zfp451^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.2x10^-5
abnormal skin morphology	1 supporting dataset	Zfp451^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp451.

Associated images

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Histopathology

There is no histopathology data found for Zfp451.

IMPC related publications

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External links

No external links available for Zfp451.

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*Zfp451^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Zfp451^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Zfp451^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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