Arid4b | AT-rich interaction domain 4B
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton Mortality/aging
15 No significant impact
3 Not tested
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
| decreased total body fat amount | 2 supporting datasets | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.11x10-11 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Arid4btm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased lean body mass | 2 supporting datasets | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.25x10-6 | ||
| increased thigmotaxis | 1 supporting dataset | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 9.74x10-6 | ||
| hyperactivity | 1 supporting dataset | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.31x10-6 | ||
| abnormal retina morphology | 1 supporting dataset | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.41x10-6 | ||
| increased bone mineral density | 1 supporting dataset | Arid4btm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.84x10-6 |
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External links
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| Arid4btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Arid4btm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Arid4btm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |