Niban1 | niban apoptosis regulator 1

GeneMGI:2137237Synonyms: Niban, Fam129a

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	2 supporting datasets	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating creatine kinase level	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.17x10^-5
enlarged heart	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged uterus	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal head size	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.79x10^-6
decreased circulating sodium level	1 supporting dataset	Niban1^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.87x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Niban1.

Associated images

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Histopathology

There is no histopathology data found for Niban1.

IMPC related publications

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External links

No external links available for Niban1.

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*Niban1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Niban1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Niban1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Niban1^{tm48482(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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