P2rx5 | purinergic receptor P2X, ligand-gated ion channel, 5

GeneMGI:2137026Synonyms: P2X5

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased exploration in new environment	1 supporting dataset	P2rx5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.98x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	P2rx5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	P2rx5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for P2rx5.

Associated images

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Histopathology

There is no histopathology data found for P2rx5.

IMPC related publications

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External links

No external links available for P2rx5.

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*P2rx5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*P2rx5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*P2rx5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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