Tm2d1 | TM2 domain containing 1

GeneMGI:2137022Synonyms: Bbp, 2310026L18Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Growth/size/body region Hematopoietic system Mortality/aging

17 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic growth retardation1 supporting datasetTm2d1em1(IMPC)BayhomozygoteE12.5N/A * 
increased hematocrit1 supporting datasetTm2d1em1(IMPC)BayheterozygoteEarly adult2.67x10-5 
embryonic growth retardation1 supporting datasetTm2d1em1(IMPC)BayheterozygoteE12.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTm2d1em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetTm2d1em1(IMPC)BayheterozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetTm2d1em1(IMPC)BayhomozygoteE12.5N/A * 
prenatal lethality1 supporting datasetTm2d1em1(IMPC)BayhomozygoteE18.5N/A * 
decreased mean corpuscular hemoglobin concentration1 supporting datasetTm2d1em1(IMPC)BayheterozygoteEarly adult1.32x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tm2d1em1(IMPC)BayExon Deletionmouse
Tm2d1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tm2d1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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