Kdm5a | lysine demethylase 5A

GeneMGI:2136980Synonyms: Rbbp2, RBP2, +1 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:1Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetKdm5aem1(IMPC)MarchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Kdm5aem1(IMPC)MarcDeletionmouse
Kdm5atm174484(L1L2_gt0_Del_LacZ)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Kdm5atm174484(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Kdm5atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kdm5atm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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